| University of Exeter Peninsula Medical School |
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University of Exeter, Peninsula Medical School (UNEXE)
Infrastructure and Resources:The Exeter Diabetes Genetics Centre (Headed by Professor Andrew Hattersley) is one of the leading international centres for basic and clinical research into diabetes. The work of the group is in 2 key areas: a) Monogenic diabetes, where the laboratory work is lead by 8a Professor Sian Ellard and the clinical aspects of this by 8b Professor Andrew Hattersley and b) Polygenic disease with an emphasis on Type 2 diabetes and related traits led by 8c Professor Tim Frayling. The key aspect of their work has been translation from gene discovery through to diagnostic testing based on findings that demonstrate a diagnosis of monogenic diabetes can alter treatment. Therefore, their work is not only on gene discovery but also on physiological and clinical studies of patients with defined monogenic diabetes looking at complications, therapy response and pharmacogenetics; establishing routine diagnostic testing and dissemination with a website which has received over 50,000 hits (www.diabetesgenes.org). The standing of this department is shown in recent awards which include the Hospital Doctor Award, the UK Academic Medicine Team of the Year and also the Queens Anniversary Prize in 2006 for excellence in higher education. In addition, Professor Hattersley Professor Sian Ellard and Professor Tim Frayling have all won national and international awards to excellence in research. The team includes 6 PIs, 5 ERs, 5 technical assistants and 4 ESRs. Infrastructure includes state-of-the-art-facilities with clinical research facility for in-patient assessment, the largest international collection of monogenic diabetes patients especially neonatal diabetes studies.
Training:The ESRs will benefit from a number of GTRS and TSRS courses including courses on monogenic and polygenic diabetes.
Partner Website:Prof. Andrew Hattersley: http://projects.exeter.ac.uk/diabetesgenes/
Publications:
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