- Andrew R Cullinane, Anna Straatman-Iwanowska, Andreas Zaucker, Yoshiyuki Wakabayashi, Christopher K Bruce, Guanmei Luo, Fatimah Rahman, Figen Gürakan, Eda Utine, Tanju B Özkan, Jonas Denecke, Jurica Vukovic, Maja Di Rocco, Hanna Mandel, Hakan Cangul, Randolph P Matthews, Steve G Thomas, Joshua Z Rappoport, Irwin M Arias, Hartwig Wolburg, A S Knisely, Deirdre A Kelly, Ferenc Müller, Eamonn R Maher & Paul Gissen
Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization
Nature Genetics, 42, (4), April 2010
- Sylvia F. Boj, Dimitri Petrov, Jorge Ferrer
Epistasis of Transcriptomes Reveals Synergism Between Transcriptional Activators Hnf1α and Hnf4α
PLoS Genetics, 2010 May 27;6(5):e1000970.
- Joris van Arensbergen, Javier García-Hurtado, Ignasi Moran, Miguel Angel Maestro, Xiaobo Xu, Mark Van de Casteele, Anouchka L. Skoudy, Matteo Palassini, Harry Heimberg, Jorge Ferrer
Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing β-cells to adopt a neural gene activity program
Genome Res. 2010 Apr 15.
- Gaulton KJ *, Nammo T *, Pasquali L *, Simon J , Giresi PG , Fogarty MP , Panhuis TM , Mieczkowski P , Secchi A , Bosco D , Berney T , Montanya E , Mohlke KL , Lieb JD , Ferrer J
A map of open chromatin in human pancreatic islets
Nat Genet. 2010 Mar;42(3):255-9. Epub 2010 Jan 31. *equal contribution
- Garin I*, Edghill E*, Akerman I*, Rubio-Cabezas O*, Rica I, Locke J, Maestro MA, Alshaikh A, Bundak R, Castillo G, Deeb A, Deiss D, Fernandez JM, Godbole K, Hussain K, O'Connell M, Klupa T, Kolouskova S, Mohsin F, Perlman K, Sumnik Z, Rial R, Ugarte E, Vasanthi T, Neonatal Diabetes International group, Johnstone K, Flanagan SE, Martínez RE, Castaño C, Patch AM Fernández-Rebollo E, Raile K, Morgan N, Harries L, Castaño L, Ellard S, Ferrer J, Perez de Nanclares G, Hattersley AT
Recessive Mutations in the INS gene result in Neonatal Diabetes through reduced insulin biosynthesis
Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3105-10 *equal contribution
- Solar M*, Cardalda C*, Houbracken I*, Martín M, Maestro M, De Medts N, Xu X, Grau V, Heimberg H, Bouwens L, Ferrer J.
Pancreatic exocrine duct cells give rise to insulin-producing ß-cells during embryogenesis but not after birth.
Dev Cell, 2009 Dec; 17 ( 6): 849-860 *equal contribution
- Servitja GM, Pignatelli M, Maestro MA, Cardalda C, Boj SF, Lozano J, Blanco E, Lafuente A, McCarthy MI, Sumoy L, Guigó R, Ferrer J.
Hnf1alpha (MODY3) controls tissue-specific transcriptiona programs and exerts opposed effects on cell growth in pancreatic islets and liver
Mol Cell Biol. 2009 Jun; 29(11):2945-59. Epub 2009 Mar 16.
- Boj SF, Servitja JM, Martin D, Rios M, Talianidis I, Guigó R, Ferrer J.
Functional targets of the monogenic diabetes transcription factors HNF1alpha and HNF4alpha are highly conserved between mice and humans
Diabetes. 2009 May; 58(5):1245-53. Epub 2009 Feb 2. *equal contribution
- Christian Sköld,, Susanne Winiwarter,, Johan Wernevik,, Fredrik Bergström,, Leif Engström,, Ruth Allen,, Karl Box,, John Comer,, Jon Mole,, Anders Hallberg,, Hans Lennernäs,, Torbjörn Lundstedt,, Anna-Lena Ungell, and, Anders Karlén
Presentation of a Structurally Diverse and Commercially Available Drug Data Set for Correlation and Benchmarking Studies
Journal of Medicinal Chemistry. 2006 49(23), 6660-6671
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